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MEDICAL NEWS · NATURE MEDICINE · 3 November 2026

Heterogeneity of microbiome responses to menopausal hormone therapy among perimenopausal women

Synopsis

Nature Medicine, Published online: 03 November 2026; doi:10.1038/s41591-026-04737-4 In this study, the gut, oral, urinary and vaginocervical microbiomes of women receiving menopausal hormone therapy were studied over 6 months, shedding light on how system metagenomics can inform clinical response and care.

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